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Faculty of Textile Engineering Labs

Laboratory of Tissue Engineering | Ft.Tul.cz

The main objectives and activities

  • Development of nano- / microfibrous and non-fibrous composite materials suitable for use in tissue engineering (replacements of cartilage, bone, blood vessels, nerve and skin tissues, glaucoma therapy)
  • Testing of cytotoxicity of materials according to standard
  • Static and dynamic biological in-vitro testing of surface and three-dimensional structures
  • Development and testing of drug delivery systems
  • Research and development of new spinning principles and technologies leading to the production of nanofibers and nanofibrous composite materials,
  • Development and production of textile composite materials for health care (wound covers, bandages, prevention of complications in colorectal surgery).

Specialization of the laboratory

  • Research and development of biodegradable and non-degradable tissue engineering carriers (intelligent wound covers, vascular replacements, bone and cartilage replacements, glaucoma implants, adhesion prevention materials and for strengthening surgical anastomoses),
  • focus mainly on nanofiber and composite materials, foams, 3D structures and linear formations,
  • For the materials produced, morphological analysis is performed using optical (including fluorescent) and electron microscopy and EDS analysis.
  • Materials are tested in-vitro using selected cell cultures (3T3, NHDF, HUVEC, MG63, HEKa) for cytotoxicity, cell adhesion, viability and cell proliferation rate (MTT assay, CCK-8 assay, fluorescence microscopy and scanning electron microscopy).

Collaborations

  • Institute of Experimental Medicine
  • AS CR
  • 2nd Faculty of Medicine
  • Third Faculty of Medicine
  • PF UPOL
  • Liberec Regional Hospital
  • Biomedical Center of the Faculty of Medicine of Charles University in Pilsen
  • Clemson University, South Carolina
  • Michigan Technological University
  • University of Alabama at Birmingham
  • ZHAW Zurich University of Applied Sciences
  • Tübingen University, Germany
  • IPF, TU Dresden, Germany
Laboratory of Tissue Engineering